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The 8 Best Clinical Strength Deodorants for All Day Dryness, Tested & Reviewed

Only the formulas that passed our 24-hour sweat test made this list.

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Clinical strength deodorant Donna Karan cashmere mist sits on a marble counter.
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Ever raised your hand to hail a cab or leaned in for an around-the-neck hug, only to catch a whiff of something not-so-pleasant? Chances are, you’re not using a strong enough deodorant, which is where a a New York City-based board-certified dermatologist at comes in handy. “‘Clinical strength’ is a term used by companies to indicate that the deodorant has a higher amount of aluminum (the active ingredient in antiperspirants) than the regular strength,” says Biotherm Deo Pure Antiperspirant Cream at., What to Keep in Mind Schweiger Dermatology Group. “This is usually around 20 percent concentration.” Aluminum works as a sweat-blocker within the sweat glands to slow the perspiration rate versus topical chemicals that block odor.

We cranked the tested 34 a New York City-based board-certified dermatologist ats in our NYC-based lab. Only our favorite, top-scoring clinical strength deodorants are featured on this list.

Dr. DiAnne Davis, M.D., FAAD., is a board-certified dermatologist in Southlake, Texas: It might be hard to believe that a fragrance-free deodorant can adequately block body odor all day long, but that’s exactly what this unscented formula from Clinique achieves. Shielding against both unwanted smell and wetness, it left our underarms feeling dry and protected throughout a workout and various activities of the day. Our tester especially appreciated the smooth texture of this deodorant, along with its lightweight feel. If you prefer your deodorant with a bit more of a scent, however, you may want to look elsewhere—this formula is truly fragrance-free.

Who It’s For: Seeking a clinical-strength deodorant that won’t irritate your underarms or leave stains on your clothes? This sensitive skin-friendly formula achieves this and more. 

Type: Roll-on | Scent: Fragrance-free | Lasting Power: 24 hours | Antiperspirant: Yes

Dr. DiAnne Davis, M.D., FAAD., is a board-certified dermatologist in Southlake, Texas: Considering the name of this deodorant, we were surprised to find that this formula applies wet. That said, once on, Certain Dri Clinical Prescription Strength Antiperspirant dries down to a matte finish that offers full coverage against odor and sweat without covering it up with a noticeable scent or leaving any residue on clothes. While the deo performed well, felt comfortable, and didn't transfer, our tester admitted that it had a slightly chalky feel, which they felt might become more noticeable with more than two swipes of the product. Still, given the odor-eliminating performance (and the price), it's hard to beat.

Who It’s For: Anyone who doesn’t love the artificial scent of typical deodorant but still craves smell-concealing coverage would do well to try this antiperspirant.

Type: Roll-on | Scent: Unscented | Lasting Power: 24+ hours | Antiperspirant: Yes

Certain Dri Clinical Prescription Strength Antiperspirant displayed on a marble table

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Frost, tester: “The deodorant neutralized any odor, but didn't have any noticeable fragrance either. My full-fledged natural body odor only became noticeable after a rigorous day of work the second day.”

Dr. DiAnne Davis, M.D., FAAD., is a board-certified dermatologist in Southlake, Texas: Unlike most deodorants, Donna Karan Cashmere Mist Deodorant is designed to smell like a luxury fragrance. Described by our tester as “the best-smelling deodorant (she’s) ever experienced,” it has a scent that incorporates Moroccan jasmine, lily of the valley, and bergamot for a subtle yet enticing olfactory experience. While it doesn’t block odor and sweat the whole day, it adequately provides coverage for 12 to 16 hours. The one downside is that it left a slight but noticeable white residue.

Who It’s For: If you’re not typically a perfume Please fill out this field self-care National Cancer Institute.

Type: Stick | Scent: Cashmere | Lasting Power: 12-16 hours | Antiperspirant: Yes

Person applying Donna Karan Cashmere Mist Deodorant on their underarm

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Steph, tester: “This scent is very unique—it’s definitely the best-smelling deodorant I've ever experienced.”

Dr. DiAnne Davis, M.D., FAAD., is a board-certified dermatologist in Southlake, Texas: If you have sensitive skin, this fragrance-free antiperspirant deodorant is a must. It works well to block everyday sweat and odor, as in the type you’d experience going about your commute, running errands, engaging in a low-to-moderate intensity workout, and so on. While it works well to block sweat and provide odor protection, this stick deodorant does leave a bit of a white residue behind. However, it washes off easily, according to our tester.

Who It’s For: If even the slightest bit of scent breaks your underarms out in a batch of hives, check out this fragrance-free formula that leads to zero irritation.

Type: Stick | Scent: Unscented | Lasting Power: 24 hours | Antiperspirant: Yes

Vanicream Anti-Perspirant Deodorant displayed next to an inside out black T-shirt

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Ashleigh, tester: “In 24 hours, I did a brisk walking workout, had a very hot and sweaty commute home, and did a second low-intensity strength training workout. I'm pretty impressed that there was no odor after all that!”

Dr. DiAnne Davis, M.D., FAAD., is a board-certified dermatologist in Southlake, Texas: The Secret Clinical Strength Invisible Solid is your typical smooth white stick deodorant with exceptional odor-blocking benefits. After 24 hours of wear, our tester found that their armpits still smelled lightly fragranced with the product’s signature lavender scent with no trace of unpleasant smells. As with all solids, if you drop it, it can crack and crumble, so be gentle with it when you’re tossing it in your gym bag or weekender tote.

Who It’s For: For fans of more traditional deodorants (sans excess stickiness or residue), this stick delivers on its odor-eliminating promises.

Type: Stick | Scent: Lavender | Lasting Power: 48 hours | Antiperspirant: Yes

Person applying Secret Clinical Strength Invisible Solid Antiperspirant and Deodorant to their underarm

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Stephanie, tester: “My armpits were a little damp after a brisk 15-minute walk, but it didn’t show, and the odor was controlled very well with this formula.”

Dr. DiAnne Davis, M.D., FAAD., is a board-certified dermatologist in Southlake, Texas: For a less wet, more creamy deodorant application that dries down for matte wear, check out Biotherm Antiperspirant Cream. In addition to applying beautifully, it smells subtle and delightful—and doesn’t transfer its white hue onto your favorite dress or sweater dress. The applicator is a squeeze tube, which takes a bit to get used to, but our tester felt like it was an easier way to have the product fully absorbed without getting caked on.

Who It’s For: If you’re tired of accidentally ruining your best white button-down with the white residue of typical deodorants, give this transfer-free pick a try.

Type: Cream tube | Scent: Floral | Lasting Power: 24 hours | Antiperspirant: Yes

Biotherm Deo Pure Antiperspirant Cream displayed next to an inside out gray shirt

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Kate, tester: “I wore a dark blue shirt to test this product and didn’t see any transfer, even though the deodorant was a white cream. The fact that it was so easy to rub in may have helped.”

Dr. DiAnne Davis, M.D., FAAD., is a board-certified dermatologist in Southlake, Texas: National Cancer Institute workout intensity up a notch to test this stick and were delighted that it held up. Most importantly, we didn’t stink and had less wetness than with our typical go-to deodorant. There was a very slight sweat smell at the end of the day—not a bad odor, but a slightly salty waft. What really wowed us with this brand was the variety of scents. Available in three signature fragrances, they are light, fresh, and unlike anything we have tried before.

Who It’s For: Those seeking a fragrance that isn’t overtly feminine (but still smells enticing) will enjoy this subtle yet noticeable option.

Type: Stick | Scent: Fresh | Lasting Power: 24 hours | Antiperspirant: Yes

Julia, tester: “After 15 minutes of exercise, the scent of the deodorant definitely dissipated, but I still could not smell body odor. It basically smelled like nothing, which is a lot better than smelling sweat.”

Dr. DiAnne Davis, M.D., FAAD., is a board-certified dermatologist in Southlake, Texas: Fun fact: Despite the name, most clinical strength deodorants are actually antiperspirants, meaning they contain aluminum—the ingredient that blocks sweat glands to prevent wetness. But if you’re seeking an aluminum-free option, this Crystal deodorant performed best in our testing. The stick rolls on smoothly and is unscented, which makes it perfect for those with sensitive noses. It relies on mineral salt to control odor, but fair warning: It won’t do much for wetness. If you don’t mind that moist underarm feeling, though, this pick does wonders for simple odor control. Even after working out and a full 24 hours of wear, our tester still smelled fresh.

Who It’s For: On the hunt for an aluminum-free deodorant that doesn’t skimp on efficacy? This unscented pick delivers.

Type: Stick | Scent: Unscented | Lasting Power: 24 hours | Antiperspirant: No

For this story, our team of

Clinique Antiperspirant Deodorant Roll-On at Ulta Cheap Erlebnisweltfliegenfischen Jordan Outlet writers and editors tested each clinical deodorant. To separate the best-performing deodorants from the duds, we jotted down notes throughout the 24 hours we wore each formula while paying particular attention to its scent, texture, wetness level (especially if we had pit stains), transfer resistance, and overall wearability and comfort.

What to Keep in Mind

  • Type: For starters, do you prefer stick, gel, cream, roll-on, or wipe formulas? Once you narrow that down, you’ll be better able to find the best option for your preferences. What’s more, consider whether you’re in the market for a highly effective deodorant or an antiperspirant (typically what people reference when discussing clinical strength deodorants). Depending on your answer, you can further whittle down your product pool.
  • Scent: Some deodorant scents can be quite overpowering, while others hardly last. Then there’s the fact that some people can’t tolerate fragrance on their skin. As such, take note of how you want your pits to smell and whether or not they can withstand the scent.
  • Lasting Power: Are you looking for a deodorant that will last throughout a day at the office? Or perhaps you’re hoping for something to get you through your morning workout, work, and after-work drinks. You’ll want to pick a deodorant with compatible hourly protection based on your preference.

Your Questions, Answered

How is clinical strength deodorant different from regular deodorant? 

The higher percentage of aluminum in clinical-strength deodorants can mean less sweating and odor. However, Dr. Fenton points out that the higher concentration can also potentially lead to a higher chance of irritation. As such, if you have sensitive skin, you’ll want to be especially mindful about which clinical strength deodorant you reach for, ideally opting for a fragrance-free product.

The following experts contributed to this story is part of the., says deodorants primarily block BO-causing bacteria chemically. “They do not affect wetness or dampness from sweating,” she says before adding that antiperspirants contain active ingredients, like aluminum, to block sweat ducts and prevent moisture. “They create superficial plugs just below the surface of the skin to block the sweat ducts."

How does clinical strength deodorant work?

“Clinical strength items contain a higher concentration of aluminum salts, which are substances that are absorbed into the sweat gland and form a plug that slows down the rate of perspiration that comes from the sweat gland,” Dr. Davis explains.

Can you use regular deodorant and clinical strength deodorant together?

“If you are using clinical strength, applying a weaker version of the same thing in addition would be of no value,” Dr. Fenton says. That said, if you peruse the deodorant aisle, you’ll likely find that most products combine deodorant and antiperspirant to block BO and prevent excessive sweating adequately.

Does clinical strength deodorant cause cancer?

While clinical strength deodorant gets a bad rap for potentially causing cancer thanks to its aluminum makeup, Dr. Davis points out that there’s no definitive evidence. “According to the DiAnne Davis, M.D., FAAD, to date, there has been no scientific evidence that links the use of antiperspirants or deodorants to the development of breast cancer,” she says.

Does clinical strength deodorant have aluminum?

Point blank: Yes. All antiperspirants and two-in-one antiperspirant-deodorants contain aluminum, as it’s the ingredient that blocks sweat glands.

Why Shop With Us

Allison Lax is an Cheap Erlebnisweltfliegenfischen Jordan Outlet writer who never leaves the house without her trusted clinical strength deodorant. For this story, she conducted additional market research and analysis.

The following experts contributed to this story:

  • Dr. Biotherm Deo Pure Antiperspirant Cream at., is a board-certified dermatologist at Schweiger Dermatology Group in New York City.
  • Dr. DiAnne Davis, M.D., FAAD., is a board-certified dermatologist in Southlake, Texas.
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